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PRODUCTS

Benfotiamine

Product name Benfotiamine
CAS No. 22457-89-2
Molecular formula C19H23N4O6PS
Molecular weight 466.4479
Structural formula
Water-solubility Dissolve in water
Appearance White crystalline powder
Use Phenylthiamine is a lipid soluble derivative of thiamine, which has higher bioavailability than thiamine. However, Phenylthiamine must be dephosphorylated by alkaline phosphatase to form a lipid soluble precursor before it can penetrate the cell membrane and exert biological effects. Clinically, it is mainly used for the treatment of diabetes complications, especially for the treatment of Chemicalbook and the prevention of diabetes retinopathy. Compared with other derivatives of thiamine, this product is absorbed more quickly and completely after oral administration. Phenylphosphorothiamine is absorbed into the systemic circulation and quickly metabolized into thiamine without increasing the drug concentration in the brain, while hippuric acid is generated and excreted through urine.

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